Tuesday, May 26, 2015

Gene Scientists' Quest for Cadaver Tissue Faces Ethical Hurdles

The Chronicle of Higher Education
May 26th, 2015

It’s one of the toughest conversations imaginable: approaching a grieving family in a hospital and asking for permission to take dozens of tissues for research from a loved one who has died unexpectedly.
During the last five years, that has been the task of "tissue requesters" operating on behalf of the Genotype-­Tissue Expression (GTEx) project, a $100-million effort organized by the National Institutes of Health. With the research — the first wave of which was published this month — scientists hope to illuminate the roles played by DNA variants in regulating the expression of genes. The researchers want to know how gene expression works in different parts of the same person’s body, and also in similar tissues across multiple individuals.

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